Researchers identify gene implicated in neuroblastoma, a childhood cancer

A new study by Mayo Clinic researchers has identified that a chromosome instability gene, USP24, is frequently missing in pediatric patients with neuroblastoma, an aggressive form of childhood cancer. The finding provides important insight into the development of this disease. The study is published in Cancer Research, the journal of the American Association for Cancer […]

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White matter changes in brain found in frontotemporal dementia

Areas of brain damage called white matter hyperintensities are commonly linked to vascular health problems. They have also been linked to Alzheimer’s disease. Now a new study has shown that white matter hyperintensities are also found in frontotemporal dementia. The study is published in the February 17, 2021, online issue of Neurology. Frontotemporal dementia, which […]

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Most teen bullying occurs among peers climbing the social ladder

Teens who bully, harass, or otherwise victimize their peers are not always lashing out in reaction to psychological problems or unhealthy home environments, but are often using aggression strategically to climb their school’s social hierarchy, a University of California, Davis, study suggests. These findings point to the reasons why most anti-bullying programs don’t work and […]

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New potential therapy for Crohn’s disease in children

Scientists from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn’s disease. This approach could become an alternative to biologic antibody therapies that carry many side effects, including increased risk of […]

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Medication keeps more patients with ANCA-associated vasculitis in remission than steroids

A Phase 3 clinical trial showed a new medication that interferes with part of the immune system that causes inflammation was more effective than treatment with glucocorticoids (“steroids” such as prednisone) in keeping patients with ANCA-associated vasculitis, a disease that causes the destructions of the body’s small blood vessels, in remission for a year. The […]

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